Toxic Metals and Autism: ASD children had 150%-to-365 % higher levels of heavy metals than controls which "corroborates data from previous studies in different parts of the world." (Not all studies have found an association between metal concentrations and ASD).
Toxic Metals and Autism Severity (I): This study "found a strong association of levels of toxic metals with variation in the degree of severity of autism." Cadmium and mercury, "were the most consistently significant."
Toxic Metals and Autism Severity (II): These data "support the historic evidence that heavy metals [including mercury and aluminum] play a role in the development of ASD," and the "toxic effect of metals increase along with the severity of symptoms."
Thimerosal Causes Autism Signs in Rats: Male pups of a certain genetic strain were most susceptible (including from post-natal exposure) to oxidative stress, motor delays and thyroid problems, all found in autism.
Thimerosal Is a "Mitochondrial Toxin":This study found a "five-fold increase in the levels of oxidant damaged mitochondrial DNA bases" from thimerosal, which "inhibits mitochondrial respiration leading to a drop in the steady state membrane potential."
Mercury/Lead Linked to ADHD: Cord blood mercury concentrations were associated with higher scores for attention problems and disruptive behavior "consistent with ADHD."
Prenatal Mercury Linked to ADHD: Mercury exposure increased inattention by 40% and impulsive/hyperactive behaviors by 70%, and were "detected primarily for boys."
ADHD Linked to Autism: This paper "provides the first genetically informative, longitudinal analysis of the interaction between traits of ASD and ADHD, and explores their genetic and environmental overlap." Its findings "add to a growing body of literature suggesting that traits of ASD and ADHD may arise via similar (causes)." Mercury and Neuroimmune Damage in Male Voles Linked to Autism:"Environmental exposure to mercury may contribute to ASD," this study said. "Mercury exposure and neuroinflammation both are implicated in certain neuropathologies (i.e., autism)." Findings were "consistent with our previously reported male-specific mercury-induced deficits in social behavior and further support a role for heavy metals exposure in autism."
"Altered heavy metals" in Autism: "Accumulation or altered mercury clearance, as well as concomitant oxidative stress... offers an intriguing component or possible mechanism for oxidative stress-mediated neurodegeneration in ASD patients."
Thimerosal Increases Glutamate in Rat Cortexes:This study concluded that "neonatal exposure to thimerosal-containing vaccines might induce excitotoxic brain injuries, leading to neurodevelopmental disorders." Thimerosal Exacerbates Other Mercury Exposures: This study found that among "nurslings whose mothers are exposed to different levels of fish mercury, a higher score of neurological development at six months was negatively associated with exposure" to thimerosal in vaccines. "Neurotoxic effects from the combined chemical forms of mercury seemed sensitive for infants exposed to additional thimerosal."
Vaccine Schedule Safety Unproven: A recent IOM paper concluded that, "All aspects of the vaccine schedule are currently under‐studied with regards to potential adverse events" including "febrile seizures or autism," and said possible studies might include "the total number of vaccines given; the average age at which the vaccines are given; or the cumulative amount of immune‐stimulating content, immunogenic adjuvants [i.e., aluminum] or preservatives [i.e., thimerosal]."
Autism Rates Fall In At Least Two States: Both Alabama and Iowa have reported declines of autism incidence by about 20%. While these apparent drops must be studied further, it's worth noting that Iowa was the first US state to ban thimerosal in vaccines.