Tuesday, June 19, 2018

500 year old prophecy on today's doctors.

Achyutananda prophecy on current doctors.
The 500 year old prophecies of Achyutananda who was an ardent devotee of Lord Jagannath and a favourite friend of Chaitanya Mahaprabhu are much feared in Odisha because they are being fulfilled with each passing day. He has predicted killing epidemics that would decimate populations.
"The death toll would be so high people would tire from cremating the bodies which would rot in homes and be eaten by dogs and other predators. The shoulders of those who carry the corpses would become sore."
"The medicines used to treat those affected," he predicts, "would further aggravate the epidemics."
For the current form of treatment and doctors he has some important words;
"Roga na chihnibe, nidana na janibe, vaidya bolaibe."
"There will emerge a group of people who will not be able to recognize the true nature of disease, who will not know anything about cures and yet they will be called doctors."
What an apt description!

Bible: Pharma is sorcery, will lead astray races.

Interesting!
The words "pharmacy" and "pharmaceutical" are derived from the Greek word, pharmakeia. This word is found in the Bible in the following passages of scripture. The Bible equates it with sorcery and points out how it will ensnare people (lead astray the races) and lead to the fall of nations. It says that those who practice pharmacy will not enter the Kingdom of God. In those who allow it to be practiced in their bodies the light of the lamp will cease to shine.
Now the deeds of the flesh are evident, which are: immorality, impurity, sensuality,
20) idolatry, sorcery (pharmakeia), enmities, strife, jealousy, outbursts of anger, disputes, dissensions, factions,
21) envying, drunkenness, carousing, and things like these, of which I forewarn you, just as I have forewarned you, that those who practice such things will not inherit the kingdom of God.
Galatians 5:19-21
and the light of a lamp will not shine in you (the great city Babylon) any longer; and the voice of the bridegroom and bride will not be heard in you any longer; for your merchants were the great men of the earth, because all the nations (ethnos) were deceived by your sorcery (pharmakeia).
Revelation 18:23
The Heritage Bible interprets the phrase "because all the nations were deceived by your pharmakeia" as "...because in your spell inducing drugs all the races were led astray"
..so that no advantage would be taken of us by Satan, for we are not ignorant of his schemes.
2 Corinthians 2:11

What does Lord Jagannath want?


The current controversies around the renowned Temple of the Lord at Puri are painful. The latest involves the keys to the jewel vault. 

The Lord has a long history. Historians describe how possibly a blue stone emerald was worshipped in ancient times at the spot by the Jains or Jina's. It was visited by many historical figures including the Pandavas. The then King of Odisha had given his daughter in marriage to Duryadhan and had fought against Krishna's army in Kurukshetra. However it was Krishna and Lakshmi that came to be worshipped in a Temple which was then on the beach. Subsequently a Temple was built further inland where the images continued to be worshipped. Later Balaram was added and Lakshmi became Subhadra, the sister of the Lord. 

The Temple was for a long time in the control of Buddhists and the Ratha Yatra symbolised the annual display of Buddha's relics. Kalapahad, a devout Hindu army leader who converted to Islam, carried out many a raid to destroy the religious structures of Odisha strangely because the Priests did not allow him to reconvert to Hinduism. On one such occasion the stone images were taken to a distant place and buried to evade harm. Over 250 years people forgot where it was hidden. Sankaracharya discovered the images through his powers and reinstated images created of Neem wood as a reflection of the tribal who had hidden Nila Madhava (relics of Sri Krishna) in a Neem tree within their realm. He also established the current form of worship based upon the highest Vedantic wisdom. 

Thus we see the entire religious history of India - Jainism Buddhism Saivism Tribal lore and Vedanta - intertwined in the worship. Saivism because Shiva is the ruling Lord of Odisha and was restablished after Buddhism degenerated into the most vile form of Hinayana Tantra. 

Lord Jagannath has been central to an extremely rich religious culture in Odisha. He remained a mute witness to all the changes that happened according to the changing mores of the Land. Today this culture stands neglected and is reflected in a crumbling society which has forgotten its rich past and is ensnared in the pursuit of money and its associated pleasures. The Temple has become a trap for devotees as they are mistreated by a group who think they have ownership over and absolute rights to the worship. 

The Lord remains a mute witness wanting nothing but perhaps pained at the developments. He has witnessed the zenith and is now witnessing the nadir. One of his hallowed devotees Achyutananda had predicted all of these 500 years ago. In a prophecy he had warned, "When the climate will play havoc disappointing the farmers, when wild animals will enter villages and towns, when Lord Jagannath will be the centre of controversies and will face infamy, know that the end of civilization is near." I know that the Sankaracharya of Puri has had a vision of that end and has warned his intimate devotees. 

Therefore my brethren, all those who adore the Lord prepare for what is to come. Like the Lord remains a witness to everything you too witness the coming destruction without fear. The inevitable always happens. Pain always follows the intense seeking after pleasure. Disassociate yourselves and study Vedanta to try and adopt the witness mode of the Self. That is what the Lord requires of us now. The survivors, as we already know will relocate him to Chhatia and we will all continue to witness His Leela in the next civilization that will unfold.

Vaccines: What Doctors Reveal.

“The decline in infectious diseases in developed countries had nothing to do with vaccinations, but with the decline in poverty and hunger.”
–Dr. Gerhard Buchwald, MD
“Crib death” was so infrequent in the pre-vaccination era that it was not even mentioned in the statistics, but it started to climb in the 1950s with the spread of mass vaccination against diseases of childhood.
–Harris L. Coulter, PhD
“It is pathetic and ludicrous to say we ever vanquished smallpox with vaccines, when only 10% of the population was ever vaccinated.”
–Dr. Glen Dettman
“Up to 90% of the total decline in the death rate of children between 1860-1965 because of whooping cough, scarlet fever, diphtheria, and measles occurred before the introduction of immunizations and antibiotics.” –Dr. Archie Kalokerinos, MD
“I think that no person would permit anybody to get close to them with an inoculation if they would really know how they are made, what they carry, what has been lied to them about them and what the real percent of danger is of contracting such a disease which is minimal.”
–Dr. Eva Snead
“In the Spring of 1948 measles was running in epidemic proportions in this section of the country. Our first act, then, was to have our own little daughters play with children known to be in the “contagious phase.” When the syndrome of fever, redness of the eyes and throat, catarrh [inflammation of a mucous membrane], spasmodic bronchial cough, and Koplik spots [measles skin spots] had developed and the children were obviously sick, vitamin C was started. In this experiment it was found that 1000 mg every four hours, by mouth, would modify the attack . . . When 1000 mg was given every two hours all evidence of the infection cleared in 48 hours . . . the drug (vitamin C) was given 1000 mg every 2 hours around the clock for four days . . . These little girls did not develop the measles rash during the above experiment and although exposed many times since still maintain this “immunity.”
–Fred R. Klenner, MD, “The Use of Vitamin C as an Antibiotic,” Journal of Applied Nutrition – 1953.
“In a predictable reaction to the recent measles outbreaks, both Republicans and Democrats in Congress filed a “Vaccines Saves Lives” resolution last Friday. Claiming that there is “no credible evidence” that vaccines cause “life-threatening or disabling disease,” the resolution interprets the vaccination issue as some kind of national security threat—thereby supposedly trumping your right to make informed decisions about your own and your children’s health. If passed, this resolution will bolster the current backlash against vaccine exemptions and pave the way for states’ efforts to mandate universal vaccinations.”
–Alliance for Natural Health – February, 2015.
“The greatest threat of childhood diseases lies in the dangerous and ineffectual efforts made to prevent them through mass immunization…. There is no convincing scientific evidence that mass inoculations can be credited with eliminating any childhood disease.”
–Dr. Robert Mendelsohn, MD
“Official data shows that large scale vaccination has failed to obtain any significant improvement of the diseases against which they were supposed to provide protection”
–Dr. Sabin, developer of Polio vaccine.
“There is a great deal of evidence to prove that immunization of children does more harm than good.”
–Dr. J. Anthony Morris (formerly Chief Vaccine Control Officer at the US Federal Drug Admin.)
“My suspicion, which is shared by others in my profession, is that the nearly 10,000 SIDS deaths that occur in the United States each year are related to one or more of the vaccines that are routinely given children. The pertussis vaccine is the most likely villain, but it could also be one or more of the others.”
–Dr. Mendelsohn, MD
“The medical authorities keep lying. Vaccination has been a disaster on the immune system. It actually causes a lot of illnesses. We are changing our genetic code through vaccination.”
–Guylaine Lanctot M.D., author of the best-seller ‘Medical Mafia’
” You can’t vaccinate believing that your children are protected and then feel that your children are not protected because somehow, some non-vaccinated child is carrying some secret organism that no one else is carrying. It just doesn’t make any sense.”
–Dr. Larry Palevsky, board-certified pediatrician
“My data proves that the studies used to support immunization are so flawed that it is impossible to say if immunization provides a net benefit to anyone or to society in general. This question can only be determined by proper studies which have never been performed. The flaw of previous studies is that there was no long term follow up and chronic toxicity was not looked at. The American Society of Microbiology has promoted my research…and thus acknowledges the need for proper studies.”
–John B.Classen, M.D., M.B.A.
“If vaccines were good for us, there would be no reason for dishonesty and deceit.”
–Joseph Mercola, DO
“No batch of vaccine can be proved safe before it is given to children.”
— Surgeon General of the United States, Leonard Scheele, addressing an AMA convention in 1955.
“Congress needs to face the facts about vaccines. They are not 100% safe—nor are they guaranteed to stop diseases. From 2005 to 2014, no child in America died from measles, yet 108 babies died from the MMR (mumps, measles, rubella) vaccine. There is also an abundance of evidence that shows the dangers of exposure to even small amounts of mercury, which can still be found in flu vaccines. Mercury has been linked to severe neurological effects and even autism. Despite the widely touted belief that the link between vaccines and autism has been “debunked,” researchers found eighty-three cases of autism among those compensated by the Vaccine Injury Compensation Program for vaccine-induced brain damage.”
–Alliance for Natural Health – 2015.
“We predict that after a long disease-free period, the introduction of infection will lead to far larger epidemics than that predicted by standard models. “Large-scale epidemics can arise with the first substantial epidemic not arising until 52 years after the vaccination program has begun.” [Guess what year 52 years from first created and licensed measles vaccine? 2015.]
–J.M. Herrernan Ph.D – 2009.
“Everyday millions of children are lined up and injected with toxic putrid substances grown on animal organs, cancer cells, aborted fetuses and other toxic substances. Few people are questioning how those viruses were obtained and how they were grown in a laboratory. If one would ask these sensible questions, one would become very enlightened about vaccine production. I warn you now, discussing vaccine-production will turn your stomach. Vaccines are made from the most vilest and filthiest substances on the earth. Since the definition of abomination is “anything that is filthy”, the term describes vaccinations adequately and truthfully. The vaccine “cauldron” is full of putrid junk from bodies exposed to disease and excreting morbid purulence. Science gathers this junk up in hopes of making vaccines for “preventing” disease; and we are being fooled while vaccinations cause increases in diseases.”
–Dr. Joseph Mercola
“The fact is that many countries that call themselves free succumbed to medical dictatorship…people are sicker and less healthy…A country which mandates vaccination is not a free country…It is a country of zombies who do what they are told by vested interests who intimidate them and use them to make money.”
–Dr. Viera Scheibner
“Parents are frightened into having their babies and children “immunized” against a whole series of diseases, having them inoculated with vaccines, serums, anti-toxins and toxoids of all kinds. The constant stream of propaganda carried on by the pharmaceutical houses and commercial medicine to keep this profitable business alive is filled with manufactured and “doctored” statistics, lies, distortions and statements designed to frighten parents. The whole purpose of this propaganda is not to secure the health and welfare of children, but to guarantee the steady inflow of profits to the physicians and manufacturing drug houses.”
–Dr. Herbert Shelton
“There is no evidence whatsoever of the ability of vaccines to prevent any diseases. To the contrary, there is a great wealth of evidence that they cause serious side effects.”
–Dr. Viera Scheibner
“[Vaccines] can have tumorigenic kidney cells of a cocker spaniel in it. It can have human fetal cells with retroviruses. [It can have] aluminum, which is one of the most horrible things to inject into any sort of life form, especially into a muscle… Parents really need to know that their doctors are not informed and therefore they cannot give informed consent, and that they really need to think about it because you cannot unvaccinate. The fear of, “Oh, what if my child gets a disease”—that’s where knowing the history is really important because what we’re talking about is under which conditions people become susceptible . That’s really more important than transmission. Because, yes, measles transmits very rapidly through the population, but it actually has a lot of benefits to the immune system—so much so that they’re using it to treat cancer today.”
–Suzanne Humphries, MD
“The explanation of an epidemic is simple, we are now seeing: 1 in 6 children with specific learning disabilities; 12-15% children with attention deficit disorder; 1 in 87 with autism spectrum – a 1700% increase over ten years; 1% sudden infant death; 40 deaths and 15,000 substantive adverse Gardasil reactions; 1 in 15 over 65 with dementia; 1 in 8 over 85; Chronic fatigue syndrome; Fibromyalgia; Seizure disorders; “West” syndrome
Global developmental delay; 1 in 450 with type 1 diabetes; 1 in 2 men and 1 in 3 women will develop cancer over a lifetime; Gulf war syndrome affecting and disabling 250,000 troops and 42,000 deaths. These vaccinated soldiers show the exact same neurological damages after vaccination as the infants and children are exhibiting after each childhood vaccination. These are strokes – oxygen demand exceeding oxygen supply – conclusively! There is no such thing as an acquired genetic epidemic. The epidemic is an acquired phenomenon, from environmental factors, for which I can now conclusively show, vaccinations are the mass culprit for most of this.”
–Dr. Andrew Moulden, PhD
Vaccination Quotes From Experts: http://bit.ly/2uNUl6H
https://steemit.com/health/@holisticgreen/doctors-who-explain-clearly-why-vaccines-aren-t-safe-or-effective

AAHS: The real toxic aluminium in vaccines!

In Merck’s Dirty Little SecretDr. Suzanne Humphries wonders why Gardasil hits the immune systems of some of these teenagers so ‘viciously,’
“By Merck’s own admission for every 100,000 people who use Gardasil or Gardasil 9 you expect a minimum of 2300 serious adverse events to combat 12 potential cases of cervical cancer.”
A vial of Gardasil contains AAHS or amorphous aluminium hydroxyphospate sulphate chosen because it ‘binds better to the protein antigen and promotes a bigger immune system bonfire with more antibodies.’
Dr. Humphries states that although she always knew that no child can be standardized, she used to believe that vaccines could be, and claims that we cannot be sure that what is printed on the vaccine label matches what is actually in the vaccine.
Dr. Humphries explains the research done by Shirodkar in 1990 in which the whole-cell DPT vaccine label manufactured by Connaught Laboratories listed the adjuvant as ‘aluminium potassium sulphate’ but was really ‘amorphous aluminium hydroxyphosphate sulphate’ or AAHS, the same adjuvant used in Gardasil.
The diptheria and tetanus toxoids that make up the highly problematic whole cell diptheria, pertussis and tetanus vaccines contain the same adjuvant AAHS as is used today in Gardasil.
Could it be that the aluminium might have played a role in the reactions said to be because of the pertussis endotoxin in the whole cell DPT vaccines? Interestingly, there were many reactions in children who were given just the diptheria and tetanus toxoid vaccines. These vaccines did not contain the pertussis endotoxin.

More Dirty Secrets

A New Zealand hepatitis B package insert from 1987 states that the adjuvant used was aluminium hydroxide. However the labelling was wrong and had to be changed to amorphous aluminium hydroxyphosphate meaning that the hepatitis B vaccines were mislabeled for more than a decade and in reality, contained a more reactive adjuvant and one that was difficult to standardize.
Another example was the misspelling of New Zealand’s VAQTA or the Hepatitis A vaccine.  The 1994 package stated that it contained aluminium hydroxide. However this was incorrect with Merck requesting the label be changed to reflect that the vaccine contained amorphous aluminium hydroxyphospate sulphate or AAHS.  And remember these adjuvants react differently in the body so it is vital that labels are  correct.
We now know that Merck’s vaccines have always contained AAHS in them.
For decades these labels have been incorrect.
Dr. Humphries explains an important implication and one that nullifies the Cochrane Review into aluminium.
In 2004 a Cochrane review of aluminium was undertaken and published in The Lancet,
“We found no evidence that aluminium salts in vaccines cause any serious or long-lasting adverse events. Despite a lack of good-quality evidence we do not recommend that any further research on this topic is undertaken.”
But as Dr. Humphries points out, these reviews were performed on aluminium hydroxide or aluminium phosphate where in reality the vaccines contained amorphous aluminium hydroxyphosphate sulphate or AAHS.
“The fact is that by 2004 vaccine manufacturers knew full well that the labelling was false and never informed.”
– Dr. Thomas Jefferson
 http://australiannationalreview.com/2018/06/17/one-vaccine-vial-is-not-necessarily-the-same-as-the-next/?inf_contact_key=c10caeb81792d64e32409c6b9203bd101a2d501c08f49c612a0d9833508bb85d

How Viruses Benefit Plants, Animals, Human

Why viruses deserve a better reputation

Sure they cause disease, but the microbes can be a help as well. Witness long-lasting pepper seeds, drought-resistant crop plants and even our own placentas.
And do we know how many viruses are bad, good or neutral for their host?
I like to say 1 percent are pathogens, which harm their host, but I think that’s probably a very high estimate. That’s based on early studies with simian [ape and monkey] viruses, which were studied a lot during early days in molecular virology. There were 80-something of these simian viruses they discovered and they were numbered SV1, SV2, etc. Of those, SV40 is the only one that’s had very much study done, and that’s because it turned out to be a pathogen, causing tumors in mice. None of the rest of them had any effect on the host they were tested in. That’s where I get my “about 1 percent.”
You were originally inspired by bacterial viruses, but in your research today, do you have a favorite virus, or one that particularly interests you?
They’re usually found in pretty low numbers, and we don’t know very much about what they do. In some cases, we know they benefit the plant. For example, white clover cryptic virus affects nodulation in legumes. Legumes normally form nodules of bacteria, in their roots, to help them take up nitrogen from the atmosphere. But doing so is costly for the plant. In virus-infected legumes, when there’s enough nitrogen in the soil, then they don’t form nodules, and that’s a benefit to the plant.
We’ve been studying another one called pepper cryptic virus. It’s a very hard thing to prove, but it seems like virus-infected seeds have a lot longer longevity than uninfected ones. After a couple of years, the uninfected seeds don’t germinate, whereas the infected cells last for many years.
Because these kinds of viruses are in a lot of crop plants, we think they probably confer some benefit, like perhaps that longevity, that made farmers breed and plant them during early agriculture.
What are some other ways viruses benefit their hosts?
Many plant viruses confer drought tolerance or cold tolerance to plants. We don’t always know how this works but, for example, elevated sugar is very common in virus-infected plants. More sugar would allow the plant cells to retain more water, protecting them from drought. And you know, things that are really sweet freeze slowly, so extra sugar would make plants cold-resistant.
And in animals, actually in mice, herpes viruses confer resistance against bubonic plague. That’s because the herpes virus, dormant in the mouse, turns up the mouse’s immune system and makes it better able to fight the plague.
Similarly, in people, hepatitis G virus may offer some protection against AIDS. Hepatitis G, now called pegivirus or GB virus C, is quite common in humans, and isn’t known to cause any disease. But it does affect the immune system in a variety of ways. If people are infected with hepatitis G first, and then HIV, it takes longer for it the HIV to progress to AIDS.
Virus and host

Vaccination NOT evidence based!

Disconnect between evidence & CDC claims Re: childhood vaccination schedule

http://ahrp.org/disconnect-between-evidence-cdc-claims-re-childhood-vaccination-schedule/
No field trials have compared the effectiveness and harms of all vaccines used according to various schedules listed in the recent BMJ infographic.6 12 The time for such studies is ethically and logistically past.
The full evidence base to make such complex decisions as the timing of each vaccination, in conjunction with developmental issues and the effect each vaccine has on the response to the others, is seldom fully available when vaccination schedules are devised…despite concerns about overloading infants’ immune systems we can find no evidence of harm.
However, because detailed reports for most clinical trials of vaccines are not available, and have not been independently reviewed, we cannot be certain of vaccines’ harms profiles.[Emphasis added]
The evidence base used in designing schedules is incomplete We should start by carrying out a more accurate assessment of the magnitude of disease threats. Those vaccines not targeting impending or credible threats should then be phased out or delayed. We also need randomised trials comparing different vaccination schedules to provide good quality data on the potential harms of single or multiple vaccinations. All aspects of vaccination should be monitored and assessed by independent studies.” 
(Is the Timing of Recommended Childhood Vaccines Evidence-Based?  Dr. Tom Jefferson and Dr. Vittorio Demicheli, BMJ (2016)
“Our findings show a positive correlation between the number of vaccine doses administered and the percentage of hospitalizations and deaths. Infants who receive several vaccines concurrently, as recommended by CDC, are significantly more likely to be hospitalized or die when compared with infants who receive fewer vaccines simultaneously. It also showed that reported adverse effects were more likely to lead to hospitalization or death in younger infants.
Of the 38,801 VAERS reports that we analyzed, 969 infants received two vaccine doses prior to the adverse event and 107 of those infants were hospitalized: a hospitalization rate of 11%.The hospitalization rate increased linearly from 11.0% for two doses to 23.5% for eight doses.
The mortality rate among vaccinated infants stratified by the number of vaccine doses they received. The mortality rate for infants who received five to eight vaccine doses was 5.4%; significantly higher than for infants who received one to four doses (3.6%)
(“Relative Trends In Hospitalizations And Mortality Among Infants By The Number Of Vaccine Doses And Age, Based On VAERS, 1990–2010,”  GS GoldmanNZ MillerHuman Experimental Toxicology, 2012; Journal of American Physicians and Surgeons, 2016 [Free full text of each]
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Cochrane Collaboration safety review of the MMR vaccine (2005; 2012)
The Cochrane reviewers determined that none of the studies upon which the safety of the MMR vaccine rests met the Cochrane Collaboration’s methodological criteria.
The design and reporting of safety outcomes in MMR vaccine studies, both pre- and post-marketing, are largely inadequate.”
no studies had a low risk of bias;* two studies had a moderate/unknown risk of bias;* eight studies had a High risk of bias.* All studies suffered from a lack of adequate description of exposure (vaccine content and schedules).* Another recurring problem was the failure of any study to provide descriptions of all outcomes monitored. In addition, there was an overall attrition rate of 33%.* “The methodological quality of many of the included studies made it difficult to generalise their results.”
 The review concluded: “The design and reporting of safety outcomes in MMR vaccine studies, both pre- and post-marketing, are largely inadequate…lack of clarity in reporting and systematic bias made comparability across studies and quantitative synthesis of data impossible.
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  •  When DTP and OPV were introduced in Guinea-Bissau in 1981, allocation by birthday resulted in a natural experiment of being vaccinated early or late. 
  • Between 3 and 5 months of age, children who received DTP and OPV early had 5-fold higher mortality than still unvaccinated children.
  • In the only two studies of the introduction of DTP and OPV, co-administration of OPV with DTP may have reduced the negative effects of DTP.
5 Conclusions: DTP was associated with 5-fold higher mortality than being unvaccinated. No prospective study has shown beneficial survival effects of DTP. Unfortunately, DTP is the most widely used vaccine, and the proportion who receives DTP3 is used globally as an indicator of the performance of national vaccination programs.
It should be of concern that the effect of routine vaccinations on all cause mortality was not tested in randomized trials. All currently available evidence suggests that DTP vaccine may kill more children from other causes than it saves from diphtheria, tetanus or pertussis. Though a vaccine protects children against the target disease it may simultaneously increase susceptibility to unrelated infections. [Emphasis aded]

Thursday, June 14, 2018

Vaccines and Autoimmune Diseases of the Adult



Abstract: Infectious agents contribute to the environmental factors involved in the development of autoimmune diseases possibly through molecular mimicry mechanisms. Hence, it is feasible that vaccinations may also contribute to the mosaic of autoimmunity. Evidence for the association of vaccinations and the development of these diseases is presented in this review. Infrequently reported post-vaccination autoimmune diseases include systemic lupus erythematosus, rheumatoid arthritis, inflammatory myopathies, multiple sclerosis, Guillain-Barré syndrome, and vasculitis. In addition, we will discuss macrophagic myofasciitis, aluminum containing vaccines, and the recent evidence for autoimmunity following human papilloma virus vaccine.

Introduction

Systemic and organ-specific autoimmune diseases are known to develop following infectious triggers. Recently we have suggested that certain autoimmune diseases like systemic lupus erythematosus (SLE) may result due to specific viral agents. Furthermore, the spectrum of disease may be influenced by a certain microbial agent in the genetically predisposed individual (Zandman-Goddard et al., 2009).

Vaccines are a prototypic source for natural immune stimulation, but may be involved in pathogenic disease in the setting of aberrant immune system function. Possibly, the burden on the immune system resulting from simultaneous multiple vaccines and even the different types of vaccines may also be an overwhelming challenge in the autoimmune prone individual (Shoenfeld et al., 2008). In this review, we discuss the evidence for the development of autoimmune diseases following infections and vaccinations.

While vaccinations are generally safe, warranted and have virtually eradicated endemic diseases and probably lessened morbidity and mortality, a question arises regarding the evaluation of possible autoimmune phenomena in vaccinated individuals.

Reported post-vaccination autoimmune diseases in the adult include SLE, rheumatoid arthritis (RA), inflammatory myopathies, multiple sclerosis (MS), Guillain-Barré syndrome (GBS), and vasculitis. Evidence for the association of vaccinations and the development of these diseases is presented in this review. In addition, we will discuss macrophagic myofasciitis, post aluminum containing vaccines and the recent support for autoimmunity following human papilloma virus vaccine.

The Role of Infections in the Induction of Autoimmune Diseases

Infections, including viruses, bacteria, parasites and fungi, have pivotal roles as environmental factors contributing to the mosaic of autoimmune diseases (Shoenfeld et al., 2008).

Evidence exists for the association of streptococcus pyogenes infection with the development of rheumatic fever (Cunningham et al., 1988), Trypanosoma cruzi parasitic infection and Chagas disease cardiomyopathy (Cunha-Neto et al., 1995), the spirochete Borrelia burgdorfeii and Lyme disease (Chen et al., 1999), Campylobacter jejuni infection and Guillain-Barré syndrome (Vucic et al., 2009; Khamaisi et al., 2004; Yuki, 2007), viral infections and diabetes mellitus I (Goldberg et al., 2009), Chlamydia pneumoniae and Epstein-Barr virus (EBV) and multiple sclerosis (Ercolini et al., 2009; Bagert, 2009), and EBV infection and SLE (Zandman-Goddard et al., 2009; Pender, 2003). Our group recently screened more than 1,300 patients with different autoimmune diseases and found a significant association of hepatitis C virus with other diseases including autoimmune thyroiditis, Crohn’s disease, pemphigus vulgaris, antiphospholipid syndrome, and vasculitides. In addition, in this study, EBV was found to be linked to SLE, RA, pemphigus vulgaris, giant cell arteritis, Wegener’s granulomatosis, polyarteritis nodosa, MS, Sjogren’s syndrome, and polymyositis (Kivity et al., 2009).

The Role of Vaccines in the Induction of Autoimmune Diseases
SLE

SLE patients show decreased immune responsiveness and are vulnerable for infectious diseases, due to the underlying disease and the frequent use of immunosuppressive drugs (Zandman-Goddard et al., 2005).

In studies of more than 10 patients, the reported manifestations following hepatitis B vaccination were arthritis, thrombocytopenia, demyelinating encephalitis, and demyelinating neuropathy. A case-control study of 265 newly diagnosed lupus patients did not show that HBV vaccine was a risk factor for developing SLE [odds ratio (OR)-1.4] (Schattner, 2005). In a current study, 10 lupus patients were diagnosed within several days and up to one year following hepatitis B vaccination (Agmon-Levin et al., 2009). Previously, 11 cases were reported in the literature regarding the onset or exacerbation of SLE post hepatitis B vaccination (Schattner, 2005).

In concordance, a latency period of less than one week and up to 2 years between vaccination and SLE onset was reported. The classical period between vaccination and autoimmunity was considered to be several weeks, similarly to the time frame suggested in the past for post-infectious autoimmunity phenomena. Interestingly, in this case series, 70% of patients continued their immunization protocol although adverse events were documented. Similarly, in previously reported cases, the affected subjects continued to be vaccinated and aggravation of their condition by additional doses was documented (Agmon-Levin et al., 2009). Overall, SLE patients presented post hepatitis B vaccination with mild to moderate disease and without life threatening organ involvement.

A summary of the serious autoimmune adverse events following vaccination with hepatitis B vaccination reported to the vaccine adverse events reporting system (VAERS) include in descending order by odds ratio: RA (OR-18), optic neuritis (OR-14), SLE (OR-9.1), alopecia (OR-7.2), MS (OR-5.2), and vasculitis (OR-2.6). Many of the adverse events associated with hepatitis B vaccination were extra-hepatic and are manifestations of infection with HBV. In addition to the potential epitopes in the HBsAg (HBV surface antigen) vaccine, adjuvants containing aluminum and mercury may provide potential antigenic stimulation (Geier et al., 2005).

Routine influenza vaccination of SLE patients seems indicated although the activation of an autoimmune response is feasible. Of 10 studies on 265 SLE patients that received influenza vaccine (with a follow-up period of 4-24 weeks) only 6 were reported to develop a flare, of those two patients had renal involvement (Conti et al., 2008; Del Porto et al., 2008; Holvast et al., 2007; Abu-Shakra et al., 2007). It is not clear that the composition of the modern vaccines is identical to those of over 30 years ago when most of the studies were performed.

In SLE, the immune response to influenza vaccination led to a blunted humoral response (Holvast et al., 2007). Generally, in the lupus patient in remission, flares are infrequent and influenza vaccine can be administered without harm. Why a few lupus patients had a flare following influenza immunization as evaluated utilizing the systemic lupus erythematosus disease activity index (SLEDAI) score is yet to be established (Abu-Shakra et al., 2007).

In a small observational study on 24 lupus patients, the 23 serotype pneumococcal vaccine did not confer disease activity (Elkayam et al., 2005).

Multiple sclerosis

Neurological manifestations are common following vaccinations (Huynh et al., 2008). In a case-control epidemiological study for serious adverse events reported in the hepatitis B vaccination exposed group compared to those that received tetanus vaccine, MS was prominent with an odds ratio of 5.2 (P<0.0003). Optic neuritis was also very commonly encountered (OR-14, p<0.0002) (Geier et al., 2005).

Guillain-Barré syndrome

In GBS, activated macrophages invade intact myelin sheaths resulting in myelin damage and demyelination (Vucic et al., 2009).

Vaccines reported as associated with GBS are diverse (Schonberger et al., 1979; Hemachudha et al., 1988; Khamaisi et al., 2004; CDC, 2006; Slade et al., 2009; Haber et al., 2009). The evidence of casual relationship with GBS is strongest with the swine flu (H1N1) vaccine that was used in 1976-7. An increased relative risk [relative risk (RR)-4-8] to develop GBS 6-8 weeks after the injection was encountered in the vaccinated group compared to the non vaccinated group. The risk for GBS was slightly less than 1 excess case of GBS per 100,000 vaccinated individuals, and hence the vaccine program was suspended (Schonberger et al., 1979). Further studies substantiated the association between the H1N1 vaccine and an increased relative risk (RR-7/1) for GBS 6 weeks after the vaccine (Safranek et al., 1991). The pathophysiology is unclear but may be related to vaccine induced anti-ganglioside antibodies (GM1) (Nachamkin et al., 2008).

Studies of influenza vaccines in the following years were not associated with a substantial increase in the rate of GBS (Lasky et al., 1998). Immunizing patients with a history of GBS requires caution.

An increased risk for GBS was found in Semple and SMB rabies vaccines. The vaccine most probably included brain protein that could cause cross reactive antibodies to the neural tissue and were discontinued. The current rabies vaccines are derived from chick embryo cells and are not associated with an increased rate of GBS (Hemachudha et al., 1988).

The vaccine against Neisseria meningitides is indicated for individuals aged 11-55 years old. The VAERS published a warning of a possible association between the Meningococcal Polisaccharide Diphteria Toxoid Conjugated Vaccine (MCV4) and GBS, because of 5 cases of GBS following the MCV4 vaccine, and later 12 additional cases were reported (CDC, 2005). Based on reports, statistical analysis did not show any significant increase in the rate of GBS occurring 6 weeks after the MCV4 vaccine compared to non-vaccinated population. However, it is recommended that individuals with a history of GBS should not be vaccinated with MCV4 unless they are in a high risk for meningococcal infection. In a mass meningococcal C conjugate vaccine (CMCV not MCV4) campaign in Quebec, Canada in 2001, 2 cases of GBS 8 weeks after the vaccine were identified among 1.5 million administered vaccinations, a rate expected in the healthy normal population (De Wals et al., 2008).

The FDA licensed the quadrivalent human papillomavirus recombinant vaccine (qHPV) in the United States in June 2006 for use in females 9-26 years old. In a review of the adverse effects reported over two years to the VAERS (Slade et al., 2009), 12 of 42 cases reported as GBS were confirmed, 11 of them in the age 13-30 years old. Only eight of the confirmed cases were in the range of 4-42 days post vaccination. The relative risk in 9-26 year old females vaccinated with qHPV vaccine for GBS was low (Callreus et al., 2009).

Vaccine induced myopathies

The reports on vaccine induced inflammatory myopathies are sporadic and include cases following immunization with HBV, bacillus Calmette-Guérin, tetanus, influenza, smallpox, polio, diphtheria, or combinations with diphtheria (Orbach et al., 2009). There is no statistically significant increase in the incidence of polymyositis or dermatomyositis after any mass vaccination. Among 289 patients with inflammatory myopathies followed in the Mayo Clinic, no recent immunization was recorded (Winkelman, 1968; Winkelmann, 1982).

Macrophagic myofasciitis

Macrophagic myofasciitis is a reaction to intramuscular injections of vaccines containing aluminum hydroxide as an adjuvant and affects mainly adults. The symptoms are usually myalgia, arthralgia, asthenia and, less frequently, muscle weakness and fever, in the presence of elevated creatine kinase and erythrocyte sedimentation rates. The electromyogram has a unique pathologic pattern characterized mainly by focal infiltration of the epimysium, perimysium, and perifascicular endomysium by sheets of large, non-epithelioid macrophages, which show fine granular staining for periodic acid-Schiff (PAS) stain that appear as small, osmiophilic, spiky structures on electron microscopy, representing the aluminum hydroxide crystals (Gherardi et al., 2001). Immunizations containing aluminum may trigger macrophagic myofasciitis in the context of an HLA-DRB1*01 genetic background (Guis et al., 2002). Frequently, patients improve with steroid therapy.

Vasculitis

Numerous case reports reported a possible association between polyarteritis nodosa (PAN) and hepatitis B vaccination. Overall, 25 cases of PAN were submitted to VAERS over an 11 year period until 2001. Among them, only 10 individuals were diagnosed as definite or possible PAN and are discussed here. The median age of patients was 45 years old and 5 patients were hospitalized. A modal peak of 2 weeks and median of 2.8 weeks post-vaccination was noted. All cases received at least 2 doses of vaccine prior to symptom onset. Hepatitis B surface antigenemia frequently follows hepatitis B vaccination and is detected many days after the 20 microgram vaccine. This could explain related immune-complex disease. Recently, there were less than 20 reports on the development of vasculitis following influenza vaccination. Small, medium, and large vessels were involved (Begier et al., 2004). All in all, this would be considered a rare event.

Rheumatoid arthritis

A total of 48 out of 898 (5.3%) of patients with early inflammatory polyarthritis reported an immunization in the 5 weeks prior to symptom onset. There were no important clinical or demographic differences between the 48 immunized patients and 185 consecutive patients who did not report prior immunization. The frequencies of HLA DRB1 *01 and *04 and the shared epitope in 33 of the immunized patients were no different in the non-immunized patients compared to healthy controls. Possibly, in a small number of susceptible individuals, immunization may act as a trigger for RA (Harrison et al., 1997).

Seropositive HLA-DR4-positive RA was reported in a few case reports after hepatitis B vaccination. In a series of 11 patients who developed RA after hepatitis B vaccination, all individuals were healthy prior to vaccination and they developed persistent polyarthritis fulfilling the present American College of Rheumatology criteria for RA (Pope et al., 1998). Five subjects expressed HLA-DR4, and HLA class II genes with the RA shared motif were identified in nine of 11 patients. In a case-control epidemiological study, adults receiving hepatitis B vaccination had an odds ratio of 18 to develop RA (P<0.0001) (Geier et al., 2005). However, the available data suggests a benefit of the vaccine that outweighs the risk (Sibilia et al., 2002).

RA patients have almost a doubled risk level of developing an infection in comparison with age- and sex-matched subjects. In two randomized studies on RA patients, a good safety profile for the influenza vaccine without an increased rate of exacerbation was shown (Conti et al., 2008). Ninety nine adalimumab treated patients had a less significant immune response than 99 placebo treated RA, but the difference was not statistically relevant (Kaine et al., 2007). Infliximab and etanercept did not influence the immunogenicity of influenza vaccine (Kubota et al., 2007). The effect of rituximab on the efficacy and immunogenicity of influenza vaccine was studied in 14 RA patients. During the 4-week follow-up after vaccination, there was no difference in disease activity in both groups of patients. In the rituximab treated patients, the percentage of responders was low for all three antigens tested, achieving statistical significance for the California antigen (Oren et al., 2008).

The safety profile of pneumococcal vaccine was good without exacerbations of RA (Elkayam et al., 2002). In 5 studies on the immunogenicity of the pneumococcal vaccine in RA patients, elevated titers of antibodies occurred but the response was partial. In 11 RA patients treated with TNF-α blockers, the titer of the antibodies increased to a lower level compared to other disease modifying anti-rheumatic drugs (DMARDs) treated RA patients. In another study, methotrexate treated patients had an inferior increase in antibodies to the 23F and B6 serotypes when compared to patients treated by TNF-α blockers and healthy controls. In the ASPIRE trial, 70 RA patients with early disease were immunized by pneumococcal vaccine 34 weeks after initiating therapy. The percentage of patients with antibody response was similar in the three groups (infliximab at 2 different doses with methotrexate or methotrexate alone) (20-25% response). All treatment groups had a lower response to vaccine than would be expected in the normal population. Interestingly, the addition of infliximab to methotrexate therapy did not impair the immune response (Visvanathan et al., 2007).

Hepatitis B vaccination was safe in 22 RA patients compared to controls without any evidence of exacerbation of the disease and was effective in 68% of patients (Elkayam et al., 2002).

HPV vaccine and autoimmune manifestations

The recently released vaccine for human papillomavirus (HPV) offers an opportunity to assess the development of autoimmune phenomena in a high risk population of young women. Hence, we chose to investigate and report separately on this vaccine.

Recently developed vaccines against human papillomavirus (HPV) and hepatitis B virus (HBV) contain a novel Adjuvant System, AS04, which is composed of 3-O-desacyl-4′ monophosphoryl lipid A and aluminum salts. All randomized, controlled trials of HPV-16/18, herpes simplex virus (HSV), and HBV vaccines were analyzed in an integrated analysis of individual data (N = 68,512). A separate analysis of the HPV-16/18 vaccine trials alone was also undertaken (N = 39,160). The reported rates of overall autoimmune events were around 0.5% and did not differ between the AS04 and control groups. The relative risk (AS04/control) of experiencing any autoimmune event was 0.98 (95% confidence intervals 0.80, 1.21) in the integrated analysis and 0.92 (0.70, 1.22) in the HPV-16/18 vaccine analysis. This integrated analysis of over 68,000 participants who received AS04 adjuvant vaccines or controls demonstrated a low rate of autoimmune disorders, without evidence of an increase in relative risk associated with AS04 adjuvanted vaccines (Verstraeten et al., 2008).

In the Danish Civil Registration system, among approximately half a million adolescent girls, 414 autoimmune disorders were listed. The 5 most common autoimmune diseases occurring within 6 weeks of vaccination among 100,000 girls were: type I diabetes, juvenile arthritis, Crohn’s disease, Henoch-Schonlein disease, and ulcerative colitis (Sutton et al., 2009). However, over a 10 year period, the common autoimmune diseases, from the most to the least common, were: type I diabetes, juvenile arthritis, Crohn’s disease, ulcerative colitis, Basedow’s disease, Henoch-Schonlein purpura, psoriasis, and SLE (Verstraeten et al., 2008).

Adverse events of potential autoimmune etiology for HPV 16/18, HBV, and genital HSV vaccine trials (n = 42) were evaluated in an integrated analysis of 68,512 individuals. Common to these 3 vaccines is their adjuvant, ASO4. A separate analysis of HPV 16/18 vaccine trials was performed in an integrated analysis of 39,160 individuals. The analysis included all completed or ongoing controlled randomized studies of the 3 vaccines conducted by GlaxoSmithKline Biologicals or collaborators. No independent sources on this subject were retrieved in a literature search. The control group received vaccines that were ASO4 free, non-adjuvanted, or adjuvanted with aluminum or aluminum hydroxide. To be included in the analysis, each individual received at least one dose of vaccine. The mean follow-up period was 1.8 years. These studies were not specifically set up to evaluate the development of autoimmune phenomena. A total of 362 participants reported at least one autoimmune event with an event rate of 0.52% in the vaccinated group which did not differ from the control group (0.54%). Hypothyroidism was the most common individual event, followed by unclassified musculoskeletal and neuroinflammatory disorders.

The overall relative risk for developing an autoimmune disease was 0.98, hence no direct statistically significant difference between the groups was encountered. However, when looking at each disease individually, the highest relative risk for an individual event was idiopathic thrombocytopenic purpura (RR-3.74), followed by SLE (RR-3.00). For organ specific disease, thyroid involvement was most commonly detected. For analysis of the entire database which included data for HBV and HSV vaccine as well, the highest relative risk for an individual event was for SLE (RR-2.39) (Verstraeten et al., 2008).

Discussion

Autoimmune diseases that are known to be infection induced and can be prevented by proper therapy in most cases include rheumatic fever and Lyme disease. A most probable causality occurred between exposure to swine flu vaccine and the development of GBS. In addition, MMF occurred following exposure to aluminum containing adjuvant. Vaccines, like infections, activate immune mediated mechanisms to induce a protective effect. Hence, a complex vaccine may theoretically be more immunogenic than a simple vaccine. Vaccines harbor added complex agents, for example, adjuvants including aluminum, which may induce autoimmune disease. Preservatives are more often found in viral vaccines compared to bacterial vaccines suggesting that the preservatives may be the inciting culprits (Israeli et al., 2009).

Given the background incidence of autoimmune disorders in some of the groups targeted for immunization with these vaccines, it is likely that autoimmune events will be reported in temporal association with vaccination, even in the absence of a causal relationship (Table 1).

http://www.discoverymedicine.com/Hedi-Orbach/2010/02/04/vaccines-and-autoimmune-diseases-of-the-adult/

Jason Christoff: MTHFR Gene Alone NOT Responsible for Autism


The MTHFR Gene and Autism
Someone tells me yesterday that Autism is caused by a defect in the MTHFR gene and not by vaccines. I wanted to help this person understand what's going on so I took great care with the conversation that followed. A default in that gene is linked to a malfunction in how the body clears heavy metals from the system and in turn those heavy metals (that continue to circulate in the blood stream) can cause the neurological damage known as Autism.
I then ask, "how do you know this faulty MTHFR gene is associated with an increased chance of Autism?" and the person replies, "because I know a friend, who has children with Autism, who tested positive for it and their doctor concluded it was the gene that caused the Autism and not the vaccine." I then clarify, "so a test exists to see if you lack a gene that helps you clear heavy metals from your body?" and this person confirms "yes, there is...". I then ask, "So why don't you think any doctor you know conducts this MTHFR test BEFORE they vaccinate children with heavy metal containing vaccines when those heavy metals are proven to cause Autism if that gene defect is present?"
Their answer........crickets, the silence was deafening.
And that's when a thinking person (ready to break out of the consensus trance) realizes that something isn't quite right with the act of NOT investigating children before they're brain damaged from heavy metals in vaccines, as compared to blaming everything else (other than the vaccine) after the child experiences vaccine induced brain damage. Other pertinent questions are 1) why are there heavy metals in vaccines in the first place, when they're proven to cause brain damage and 2) are we really to believe that a perfect functioning gene (of any kind) can somehow protect a child from toxic aluminum or mercury in vaccines, when both compounds carry the scientific classification of "genetic terminator", meaning they terminate ALL life in EVERY cell they come into contact with. Please produce for me the study that proves there exists a gene that can detox mercury and aluminum, rendering injections of mercury or aluminum perfectly safe and benign? Connect the dots. It's an ambush. Protect the children from the order followers and the evil invisible hand that puppeteers them from high atop the eugenic ruling pyramid. The truth is simple. Inept people have been hand picked to govern almost every aspect of our lives, because chaos is a business model, which not only increases profit but also maintains control over a bewildered and dis-empowered slave class. It's a farm, a human farm. We're the animals and as any farmer will tell you, "you can't farm lions, only lambs" because lambs are weak and can't resist the farmer when slaughter time comes around. The toxic applications of our farmers (everything from poisonous vaccines to toxic medications and from GMO foods to fluoride) keeps us in the exact weakened state needed for perpetual slaughter.
Here we see how aluminum in vaccines causes brain damage. http://bit.ly/1O8c4VQ
Here we see how mercury in vaccines causes brain damage.http://bit.ly/1NtU5O5
Here we see how each and every vaccine, causes some form of brain damage, in each and every person injected....no exceptions. https://bit.ly/2i4N6zG
At this added link over 100 medical doctors and scientists explain why vaccines aren't safe or effective. http://bit.ly/1qX8HMV
The government and vaccine manufacturers have already admitted legally that vaccines do cause the brain damage known as Autism. Only the public seems confused about this. https://bit.ly/2FDVS2C
At this added link https://bit.ly/2c9tf0z Dr. James Chestnut explains CLEARLY that genes actually control nothing directly in our body and therefore by blaming disease on genes (and not the environment that is proven to control the genes), helps an entire society deflect as to why the children are really sick. Our children are sick because of what we're being tricked to do to them by extremely corrupt forces within science, medicine and govenrment. The genes aren't making our children sick, we are, and that means we can also make our children healthy.......but we need to stop poisoning them first. It's that simple.